Wednesday, 30 October 2013

Dhoom 3 trailer: Aamir Khan in a never before avatar as clown thief sahir


The slick and super stylish trailer is quite a thrill to watch with sharp dialogues and exciting background score. The visuals are stunning. 
Going by the trailer, the film looks very promising and will surely live up to the expectations. 

Aamir Khan is playing a negative character for the first time. His character is Sahir - the clown thief.


According to the reports, Aamir will be seen in a never before avatar. He will also be travelling in time in the film. His portions have been shot discreetly and the entire cast and crew are tight lipped about it.
Not only this, there are also rumours that he will be seen in a double role in the film. Aamir will romance Katrina Kaif who is looking glamourous as ever.
Apart from Aamir Khan and Katrina Kaif, both Abhishek Bachchan and Uday Chopra will continue in their now iconic roles of Jai Dixit and Ali from the previous two movies of the franchise.
The film will be released on December 20, 2013.

Tuesday, 22 October 2013

SLEEP

If you don't get enough sleep per day (8+ hours), your desires will increase for cheating, lying and stealing

POPULATION

If we could shrink the world's population to a village of 100 people, we would have: 57 Asians, 21 Europeans, 14 Americans & 8 Africans.

Sunday, 20 October 2013

 

PARACETAMOL TOXICITY


     Paracetamol toxicity is caused by excessive use or overdose of the analgesic drug paracetamol. Mainly causing liver injury, paracetamol toxicity is one of the most common causes of poisoning worldwide. In the United States and the United Kingdom it is the most common cause of acute liver failure.

     Many individuals with paracetamol toxicity may have no symptoms at all in the first 24 hours following overdose. Others may initially have nonspecific complaints such as vague abdominal pain and nausea. With progressive disease, signs of liver failure may develop; these include low blood sugar, low blood pH, easy bleeding, and hepatic encephalopathy. Some will spontaneously resolve, although untreated cases may result in death.

     Damage to the liver, or hepatotoxicity, results not from paracetamol itself, but from one of its metabolites, N-acetyl-p-benzoquinoneimine (NAPQI)(also known as N-acetylimidoquinone).NAPQI depletes the liver's natural antioxidant glutathione and directly damages cells in the liver, leading to liver failure. Risk factors for toxicity include excessive chronic alcohol intake, fasting or anorexia nervosa, and the use of certain drugs such as isoniazid.

     Treatment is aimed at removing the paracetamol from the body and replacing glutathione. Activated charcoal can be used to decrease absorption of paracetamol if the patient presents for treatment soon after the overdose; the antidote acetylcysteine acts as a precursor for glutathione, helping the body regenerate enough to prevent damage to the liver. N-acetylcysteine can neutralize NAPQI by itself as well. A liver transplant is often required if damage to the liver becomes severe. Patients treated early have a good prognosis, whereas patients that develop major liver abnormalities typically have a poor outcome. Efforts to prevent paracetamol overdose include limiting individual sales of the drug and combining paracetamol with methionine, which is converted into glutathione in the liver.





 

 


 THE IMPORTANCE OF JANUARY 26TH IN INDIAN HISTORY

Sher Shah defeated HUMAYUN ON January 26, 1539.

Jahangir was born on January 26,1554.

Babar died on January 26, 1580.

Nadir Shah invaded Delhi on January 26, 1539.

Tipu Sultan fought with the English on January 26, 1762.

 The sale if women in India were declared illegal on January 26, 1818.

The Telephone systems in Bombay, Calcutta and madras were started on January 26, 1816.

The Bombay High Court was set up on January26, 1869.

The first rail service from Calcutta to Bombay was started started on January 26, 1874.

Our country took the pledge of complete independence on January 26, 1930

The new Constitution of free India came into force and India was declared a republic on January 26, 1950.